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1540 Highway 501, Myrtle Beach
$2,150
2623786 MLS
These units sit on one of the busiest commercial corridors on the Grand Strand. US 501 is one of the main routes to the Grand Strand, running as a multilane highway from Myrtle Beach to Marion, so a business here is in front of both year-round residents and the constant flow of visitors. Locals consider it the primary gateway into the heart of the city. For a retail operator, that means strong drive-by visibility. For a service or light-industrial user, it means easy access for customers, deliveries, and crews heading anywhere in Horry County. The layout suits both uses. The open main floor has storefront glass on the front for display or a showroom. The rear can have a private office, a restroom, and a rear door to a patio, which works well for staff access or loading. The 590 sq ft second level adds room for storage, inventory, or additional office space without cutting into the main floor. That makes the unit a good fit for contractors, trades, e-commerce and fulfillment, specialty retail, or any small business that needs a front-of-house and back-of-house under one roof.

1540 Highway 501, Myrtle Beach

Listing courtesy of Listing Agent: Heather Rollins () from Listing Office: Barefoot Rental Management LLC.

1320 44th Ave. N Unit UNIT C, Myrtle Beach
$4,125
2620669 MLS
A fantastic opportunity to lease space in a newly constructed commercial building in a prime Myrtle Beach location. Two versatile dark-shell units are available, offering flexibility for a variety of business uses. The main building is anticipated to be completed in December 2026, providing an excellent opportunity for tenants to secure space early and customize the interior to meet their specific business needs. Tenants may lease this unit at approximately 1,500 heated square feet or combine both units for approximately 3,789 total square feet (including heated and non-heated space). The property is offered under a Triple Net Lease. The Landlord is offering a tenant improvement/build-out contribution in lieu of a traditional FF&E allowance, subject to approved plans, lease terms, landlord approval, and the allocated improvement budget.

1320 44th Ave. N Unit UNIT C, Myrtle Beach

Listing courtesy of Listing Agent: Caroline Dargan () from Listing Office: Dargan Real Estate.

1320 44th Ave. N Unit UNIT B, Myrtle Beach
$5,346
2620667 MLS
A fantastic opportunity to lease space in a newly constructed commercial building in a prime Myrtle Beach location. Two versatile dark-shell units are available, offering flexibility for a variety of business uses. The main building is anticipated to be completed in December 2026, providing an excellent opportunity for tenants to secure space early and customize the interior to meet their specific business needs. Tenants may lease one unit at approximately 1,944 heated square feet or combine both units for approximately 3,789 total square feet (including heated and non-heated space). The property is offered under a Triple Net Lease. The Landlord is offering a tenant improvement/build-out contribution in lieu of a traditional FF&E allowance, subject to approved plans, lease terms, landlord approval, and the allocated improvement budget.

1320 44th Ave. N Unit UNIT B, Myrtle Beach

Listing courtesy of Listing Agent: Caroline Dargan () from Listing Office: Dargan Real Estate.

307 Broadway St., Myrtle Beach
$149,900
2616975 MLS
Broadway Pizza & Bakery – Turnkey Restaurant Opportunity Exceptional opportunity to own Broadway Pizza & Bakery, a fully operational restaurant located at 307 Broadway Street, Myrtle Beach, SC 29577. This turnkey business features a fully equipped commercial kitchen and is ready for a new owner to step in and continue operations from day one. Ideally situated on the charming and revitalized Broadway Street, the property is just a short walk from Myrtle Beach's emerging Arts & Innovation District, Ocean Boulevard, and the world-famous Boardwalk, placing it in the heart of one of the area's most active tourism and business corridors. Surrounded by established businesses, hospitality properties, professional offices, and just minutes from the beach, this prime location benefits from strong pedestrian traffic, a growing local customer base, and year-round visitor activity. Whether you're an experienced restaurateur looking to expand or an entrepreneur seeking a proven business in a thriving coastal market, Broadway Pizza & Bakery offers an outstanding opportunity in one of Myrtle Beach's most desirable commercial locations.

307 Broadway St., Myrtle Beach

Listing courtesy of Listing Agent: Liat Edri () from Listing Office: Realty ONE Group Dockside.

111 Not Specified, Myrtle Beach
$169,000
2615050 MLS
Established and award-winning carpet cleaning franchise opportunity serving the Grand Strand and surrounding areas. This turnkey Oxi Fresh Carpet Cleaning business includes protected franchise territory covering 17 zip codes throughout Myrtle Beach, North Myrtle Beach, Conway, Carolina Forest, Surfside Beach, Murrells Inlet, Pawleys Island, Little River, and surrounding communities. Sale includes two paid-off Nissan NV2000 service vans, four OF1000 carpet cleaning machines, three upholstery cleaning machines, tile and grout cleaning equipment, hydro sensors, water claw, vacuums, and all necessary tools and supplies needed to continue operations. The business benefits from national franchise support, marketing resources, centralized call center assistance, established systems, and an existing customer database. Oxi Fresh Carpet Cleaning of Myrtle Beach has earned multiple Readers' Choice Awards for Best Carpet Cleaner, including First Place recognition in 2022, 2023, and 2024, demonstrating strong community recognition and customer satisfaction. This home-based business model offers low overhead and significant growth potential for an owner-operator, entrepreneur, or existing service company seeking expansion. Franchise transfer subject to Oxi Fresh approval. Confidential sale. Financial information available to qualified buyers upon execution of a Non-Disclosure Agreement. Business Only Sale – No Real Estate Included.

111 Not Specified, Myrtle Beach

Listing courtesy of Listing Agent: Kelli Hays () from Listing Office: Realty One Group Dockside Cnwy.

TBA N Kings Highway, Myrtle Beach
$265,000
2611605 MLS
This well-established bakery and deli presents a rare opportunity to acquire a thriving, long-standing business in a highly desirable, high-traffic corridor. This year round location, just off Highway 17, is accessible for north and south bound traffic with a convenient traffic light into the plaza. With over 12 years of proven success, the business operates an approximately 2,400 square foot space and benefits from ample on-site parking, offering both convenience and accessibility for its loyal customer base. Ideally positioned along a prominent stretch of Highway 17, the location provides excellent visibility and is in close proximity to beaches, schools, and a major hospital driving consistent, year-round patronage. Renowned for its freshly made bagels and a variety of baked goods prepared daily on-site, this popular breakfast and lunch destination also features inviting outdoor seating. With a strong foundation already in place, the business offers significant potential for continued growth and expanded service offerings under new ownership.

TBA N Kings Highway, Myrtle Beach

Listing courtesy of Listing Agent: Joseph Cummings (Office: 843-903-4400) from Listing Office: CB Sea Coast Advantage CF.

Provided courtesy of The Coastal Carolinas Association of REALTORS®. Information Deemed Reliable but Not Guaranteed. Copyright 2026 of the Coastal Carolinas Association of REALTORS® MLS. All rights reserved. Information is provided exclusively for consumers’ personal, non-commercial use, that it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.