378 listings, but only 250 max can be displayed.
Sort by
2001 Ocean Blvd. S, Myrtle Beach
$2,500
2624258 MLS
Now available for lease at 2001 S Ocean Blvd, this approximately 2,200-square-foot commercial space offers a unique opportunity within the oceanfront Bluewater Resort high-rise in Myrtle Beach. Formerly utilized as professional office space, the unit features a welcoming tiled lobby, reception area, coffee bar with an existing water line, multiple private offices, a spacious bullpen/work area, and two private restrooms. The flexible layout allows the space to continue as an office or potentially accommodate a variety of retail and service-oriented concepts, including a convenience market, café, coffee shop, or breakfast concept, subject to applicable zoning and approvals. Additional resort amenities may also be negotiable, including access to a large third-floor event space featuring ocean views. The property is located within the City of Myrtle Beach and is zoned MU-H (Mixed Use High Density), offering flexibility for a range of potential uses. An added advantage is the opportunity for an all-inclusive rental structure that includes property taxes, building insurance, property maintenance, electricity, and water, providing tenants with predictable occupancy costs in a prime Ocean Boulevard location.

2001 Ocean Blvd. S, Myrtle Beach

Listing courtesy of Listing Agent: Joseph Cummings (Office: 843-903-4400) from Listing Office: CB Sea Coast Advantage CF.

4750 Hwy 17 S Unit 4583 Wesley RD, Murrells Inlet
$4,399,000
2624209 MLS
Introducing a rare 6.5-acre commercial opportunity with approximately 852' of total road frontage, giving you standout visibility and easy access. Right now, the site includes roughly 23,000 square feet under roof, across multiple large insulated metal buildings, and the approved conceptual plan adds about 14,000 more, bringing you to a potential 37,000 square feet under roof. The plan supports a versatile mix of retail, warehouse, storage, or office uses, and with several acres of open undeveloped space, there's plenty of room for future expansion, too. Bottom line: strong frontage, existing infrastructure, significant square footage, and an approved plan that supports growth- a solid opportunity whether you're an investor, owner-user, or developer.

4750 Hwy 17 S Unit 4583 Wesley RD, Murrells Inlet

Listing courtesy of Listing Agent: Drew Swinnie () from Listing Office: Carolina Gold Realty, LLC.

802 13th Ave. S, North Myrtle Beach
$999,900
2623921 MLS
Excellent opportunity to own a well-positioned commercial property in the heart of North Myrtle Beach! Located at 802 13th Avenue South, this approximately 4,638-square-foot office building sits on roughly 0.36 acres and offers outstanding visibility, convenient access, ample parking, and signage opportunities. The property offers a versatile layout suitable for a variety of professional, medical, office, or service-oriented businesses. With multiple potential office spaces, this property also presents an attractive opportunity for an owner-user looking to occupy a portion of the building while generating additional income from other occupants. Conveniently located just off Highway 17 and minutes from the beach, residential communities, shopping, dining, and everything North Myrtle Beach has to offer. Whether you are looking for a new location for your business, an investment property, or a combination of both, this commercial property offers exceptional potential in one of the Grand Strand’s most desirable and growing markets. Schedule your private showing today and explore the possibilities at 802 13th Avenue!

802 13th Ave. S, North Myrtle Beach

Listing courtesy of Listing Agent: Desiree Rowles (Cell: 843-450-2535) from Listing Office: Rowles Real Estate.

14323 Ocean Highway Unit Unit 4141, Pawleys Island
$125,000
2623919 MLS
Prime Commercial Opportunity with Immediate Passive Income in Litchfield, SC! Discover the perfect blend of coastal lifestyle and business savvy with this exceptional office condo located in the highly desirable heart of Litchfield. Situated just steps from local shops, dining, and right next to the pristine beaches of Pawleys Island, this property offers unparalleled convenience and visibility for any professional practice. Whether you are looking to expand your portfolio with an effortless, turn-key investment or secure a premium future location for your own business, this space delivers exceptional value and a highly functional layout designed to maximize operational efficiency. Regime fees are low and currently includes a reliable, long-term tenant who is eager to remain in place, offering immediate passive income from day one.

14323 Ocean Highway Unit Unit 4141, Pawleys Island

Listing courtesy of Listing Agent: David Nelson () from Listing Office: Agent Group Realty.

1011 N N Fraser St. Unit 1011 N Fraser St Georgeto, Georgetown
$6,318
2623896 MLS
Professional medical/office suite for lease in a high-visibility location on N Fraser Street (US-701) in Georgetown. This efficient ±4,212 SF space offers a functional layout with multiple private rooms ideal for exam rooms, consultations, or administrative offices, a spacious waiting/reception area, wet bar, utility room, and several restrooms. Excellent exposure, easy access, and convenient proximity to Tidelands Georgetown Memorial Hospital (less than 1 mile). Ample parking. Georgetown continues to see steady job growth and significant public infrastructure investment, supporting a strengthening local economy and expanding healthcare demand near Tidelands Georgetown Memorial Hospital. Perfect for medical practices, specialists, or professional services seeking a strategic, turnkey location. NNN lease. Current TICAM.

1011 N N Fraser St. Unit 1011 N Fraser St Georgeto, Georgetown

Listing courtesy of Listing Agent: Aaron Hutchison (Cell: 843-273-8190) from Listing Office: Carolina One Real Estate.

1107 48th Ave. N Unit Suite 310-E, Myrtle Beach
$1,435
2623886 MLS
Premier Office Suite Available at Parkway Office Plaza. Located at the signalized intersection of 48th Avenue North and Robert Grissom Parkway, Parkway Office Plaza is one of Myrtle Beach’s premier office complexes. The property offers convenient access to Highways 17 and 31, providing excellent regional connectivity for tenants, clients, and visitors. Suite 310-E at 1107 48th Avenue North features a private office, two spacious work areas, a kitchenette, and a private bathroom. The suite offers an upscale professional environment with high-end finishes, including hardwood flooring, a vaulted ceiling, stained-glass windows, chair rail, and crown molding. Janitorial services, electricity, and Wi-Fi are included with CAM, offering tenants added convenience and predictable operating expenses.

1107 48th Ave. N Unit Suite 310-E, Myrtle Beach

Listing courtesy of Listing Agent: Brad Davis () from Listing Office: Tradd Commercial.

1540 Highway 501, Myrtle Beach
$2,150
2623786 MLS
These units sit on one of the busiest commercial corridors on the Grand Strand. US 501 is one of the main routes to the Grand Strand, running as a multilane highway from Myrtle Beach to Marion, so a business here is in front of both year-round residents and the constant flow of visitors. Locals consider it the primary gateway into the heart of the city. For a retail operator, that means strong drive-by visibility. For a service or light-industrial user, it means easy access for customers, deliveries, and crews heading anywhere in Horry County. The layout suits both uses. The open main floor has storefront glass on the front for display or a showroom. The rear can have a private office, a restroom, and a rear door to a patio, which works well for staff access or loading. The 590 sq ft second level adds room for storage, inventory, or additional office space without cutting into the main floor. That makes the unit a good fit for contractors, trades, e-commerce and fulfillment, specialty retail, or any small business that needs a front-of-house and back-of-house under one roof.

1540 Highway 501, Myrtle Beach

Listing courtesy of Listing Agent: Heather Rollins () from Listing Office: Barefoot Rental Management LLC.

618 Chestnut Rd. Unit #204, Myrtle Beach
$139,900
2623732 MLS
First impressions matter in business, and this one delivers before your client even sits down. Suite 204 at 618 Chestnut Rd office spaces in Myrtle Beach, housed in a building with striking architectural character that sets the tone the moment anyone walks through the door. Located just off Highway 17, you are planting your flag in one of the most trafficked and recognizable corridors on the entire Grand Strand. The suite features a reception area, three offices, a private restroom, abundant natural light from generous windows, and 10-foot ceilings that make the space feel far larger than the square footage suggests. Turnkey and ready to operate from day one. Current building tenants include an architect, accountant, landscaping company, home care provider, real estate, and property management firms, giving the space the feel of an established professional environment. Second floor, Suite 204, accessible via two staircases. Easy access to Highway 17, Highway 31, and Highway 22. If your business deserves a space that commands attention, this is it. Schedule your tour today.

618 Chestnut Rd. Unit #204, Myrtle Beach

Listing courtesy of Listing Agent: Jeff Forman (Cell: 843-902-4325) from Listing Office: Keller Williams The Forturro Group.

618 Chestnut Rd. Unit #204, Myrtle Beach
$1,550
2623731 MLS
First impressions matter in business, and this one delivers before your client even sits down. Suite 204 at 618 Chestnut Rd office spaces in Myrtle Beach, housed in a building with striking architectural character that sets the tone the moment anyone walks through the door. Located just off Highway 17, you are planting your flag in one of the most trafficked and recognizable corridors on the entire Grand Strand. The suite features a reception area, three offices, a private restroom, abundant natural light from generous windows, and 10-foot ceilings that make the space feel far larger than the square footage suggests. Turnkey and ready to operate from day one. Current building tenants include an architect, accountant, landscaping company, home care provider, real estate, and property management firms, giving the space the feel of an established professional environment. Second floor, Suite 204, accessible via two staircases. Easy access to Highway 17, Highway 31, and Highway 22. If your business deserves a space that commands attention, this is it. Schedule your tour today.

618 Chestnut Rd. Unit #204, Myrtle Beach

Listing courtesy of Listing Agent: Jeff Forman (Cell: 843-902-4325) from Listing Office: Keller Williams The Forturro Group.

706 North Ocean Blvd. Unit Unit D, Myrtle Beach
$6,700
2623715 MLS
Turnkey Oceanfront Restaurant Opportunity on the Myrtle Beach Boardwalk Located at 706 N Ocean Blvd, Unit D, this fully built-out restaurant space offers a prime position on the Myrtle Beach Boardwalk, a high-traffic destination that welcomes an estimated 13–15 million visitors annually. The 2,680-square-foot space features oceanfront outdoor patio seating with capacity for 150+ guests. All furniture, fixtures, and equipment will remain for the tenant’s use, including tables, chairs, bar equipment, and a fully functioning kitchen with a ventilation hood. The location is within sight of major annual events, including the Carolina Country Music Festival, Boardwalk Fright Nights, Sun Fun, Winter Wonderland at the Beach, and Hot Summer Nights.

706 North Ocean Blvd. Unit Unit D, Myrtle Beach

Listing courtesy of Listing Agent: Brad Davis () from Listing Office: Tradd Commercial.

893 Gator Ln. Unit Unit A, Murrells Inlet
$355,000
2623535 MLS
Convenient location in the heart of the commercial area on Hwy 17 Bypass in Murrells Inlet. Great office space for a builder, site contactor, insurance, small legal office, etc--especially for any operation needing a little warehouse/storage space in the rear. This space, like the other two in the building, was originally an open warehouse. But a previous owner built out the inside to be a builder's office with receptionist area, conference room, two offices, two bathrooms, and a kitchen area, with a garage in the rear with floored storage area above the entire heated and cooled office area and stairs up to it from the garage area. The office could be occupied as is or easily upgraded with new carpet and paint.

893 Gator Ln. Unit Unit A, Murrells Inlet

Listing courtesy of Listing Agent: Randy Wallace (Office: 843-443-9400) from Listing Office: Keller Williams Innovate South.

1010 5th Ave. N Unit Unit 101 Suite F, Surfside Beach
$340
2623512 MLS
Introducing Ardis Offices 101 . A premier leasing opportunity in Surfside Beach, SC. This well-maintained property offers a range of amenities, including inclusive water and power, high-speed internet access, and ample parking availability. With a minimum one-year lease term and management for prompt assistance, tenants can enjoy peace of mind and convenience. Centrally located in Surfside Beach, this secure and professionally managed premises provides a prime business environment for a variety of professional endeavors. The entire space has a lobby, conference room, small kitchen area and two restrooms. Embrace the opportunity to elevate your business operations in this exceptional leasing opportunity at Ardis Offices 101.

1010 5th Ave. N Unit Unit 101 Suite F, Surfside Beach

Listing courtesy of Listing Agent: Blake Floyd () from Listing Office: Twin Oaks Real Estate, LLC.

1009 Highway 501 Unit Suite 1009 Warehouse, Myrtle Beach
$9,500
2623411 MLS
Tradewinds Plaza sits at a high-visibility intersection along US 501, one of Myrtle Beach's primary commercial corridors connecting inland traffic to the beach. The center's end-cap availability, generous parking, and strong signage exposure make it an ideal fit for retail, service, or general commercial tenants looking to establish a high-visibility presence in a fast-growing submarket. Building highlights Available Now Space Highlights 2,200 SF vanilla shell — ready for tenant build-out to suit Premium end-cap position with maximum visibility Direct frontage on US Highway 501 Major pylon/building signage available for strong brand exposure 212 shared parking spaces on-site — ample customer and employee parking Located within Tradewinds Plaza, a 47,500 SF mixed-use commercial center with strong co-tenancy and growing daily traffic counts

1009 Highway 501 Unit Suite 1009 Warehouse, Myrtle Beach

Listing courtesy of Listing Agent: Joseph Ganassa () from Listing Office: Tradd Commercial.

3751 W Palmetto St., Florence
$7,000
2623358 MLS
Position your business for success with this 4,190 SF restaurant space available for lease on a triple net basis, located just off I-95 Exit 157. This prime property features copious road frontage, two driveway entrances, and ample parking, ensuring easy access and strong visibility for both local residents and interstate travelers. With 17,800 vehicles daily on US-76 and 36,300 vehicles daily on I-95, the site offers unmatched exposure and customer flow. Surrounded by established national brands like McDonald’s, Waffle House, Circle K, QuikTrip, BP, and Super 8 by Wyndham, this location has a proven track record for restaurant, retail, and service businesses. All essential amenities are already in place, making it easy to set up quickly and start serving a steady stream of customers.

3751 W Palmetto St., Florence

Listing courtesy of Listing Agent: Brian Rodgers (Cell: 843-624-7887) from Listing Office: NorthGroup Real Estate LLC.

1608 Main St. Unit 1708 Oak St, Conway
$3,950,000
2623352 MLS
Rare opportunity to acquire a substantial medical and professional campus in the heart of Conway, SC. Situated on a combined 2.91 acres, the property offers nearly 24,000 square feet across two locations with exceptional frontage, accessibility, ample parking, and room for future growth. 1608 Main Street features approximately 12,525 square feet with 257 feet of road frontage, while 1708 Oak Street offers approximately 11,252 square feet with 405 feet of frontage. Together, the properties provide an impressive 662 feet of combined road frontage with convenient access from Main Street, Oak Street, and 17th Avenue. Currently home to Health Care Partners, the campus features a versatile mix of medical and professional space including exam rooms, private offices, administrative areas, pharmacy space, and a large auditorium/multipurpose area. A detached workshop/facility building, private fenced parking area, four existing parking areas, and additional green space further enhance the property's flexibility and potential for future expansion. Zoned NC – Neighborhood Commercial and ideally positioned along the Main Street corridor near historic Downtown Conway, this property presents an exceptional opportunity for a healthcare provider, professional or institutional organization, investor, or owner-occupant seeking a prominent presence in the growing Conway market. Health Care Partners will remain open and fully operational while its new facility is completed.

1608 Main St. Unit 1708 Oak St, Conway

Listing courtesy of Listing Agent: Camilla Johnson Nye Smith () from Listing Office: Kingston Properties.

1798 Highway 701 North, Loris
$474,999
2623348 MLS
Incredible opportunity to own a high-visibility commercial property with a fully operational convenience store and gas station located on bustling Highway 701 N in Loris. Situated on 2.45 acres, this property offers significant potential for expansion and multiple income streams. This established business features newer fuel pumps and a modernized canopy/awning, providing a fresh and professional appearance for customers. The interior offers ample retail space with room to add a hot food service area, additional coolers, or other high-demand amenities. Whether you're expanding an existing operation or launching a new venture, this space is primed for customization and growth. The generous 2.45-acre lot presents endless possibilities---subdivide the land, build additional commercial units, or develop complementary businesses such as a car wash, food trucks, or a small strip center. With excellent frontage on Highway 701, the property benefits from high daily traffic and great visibility. Don't miss this chance to invest in a thriving location with proven income and huge potential for future development. Schedule your showing today and unlock the possibilities at 1798 Highway 701 N!

1798 Highway 701 North, Loris

Listing courtesy of Listing Agent: The Mills Group Team () from Listing Office: Century 21 Barefoot Realty.

Provided courtesy of The Coastal Carolinas Association of REALTORS®. Information Deemed Reliable but Not Guaranteed. Copyright 2026 of the Coastal Carolinas Association of REALTORS® MLS. All rights reserved. Information is provided exclusively for consumers’ personal, non-commercial use, that it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.